Studies on Staphylococcal L-Forms

Studies on the Pathogenesis of Staphylococcal Infection

Necrosis of rabbit skin produced by thermal injury was found to result in a striking increase in local infectivity of staphylococci that were coagulase-positive and hemolytic, but no local increase in the infectivity of non-pathogenic staphylococci. Infection produced in necrotic burns extended beyond the area of burn and was characterized by hemorrhage, edema, and necrosis of contiguous normal...

In Vivo Studies on Staphylococcal Penicillinase.

Eyckmans, Luc (Baylor University Medical Center, Dallas, Tex.), and Ralph Tompsett. In vivo studies on staphylococcal penicillinase. J. Bacteriol. 90:589-593. 1965.-The amounts of staphylococcal penicillinase present in tissue of mice with well-established infections due to penicillin-resistant staphylococci were determined. The data indicate that, in the presence of such infection, penicillina...

Studies in Staphylococcal Fever

Despite intensive investigation of the fever caused by endotoxins of Gramnegative bacteria, the pyrogenic properties of Gram-positive bacteria appear to have attracted relatively little attention. There are scattered reports dealing with fever-inducing effects of whole cultures or culture filtrates of several Gram-positive organisms given intravenously.`6 Other investigators, however, have been...

Induction and cultivation of staphylococcal L forms in the presence of methicillin.

Studies of L Forms and Protoplasts of Group a Streptococci

Intact bacterial membranes have been isolated from protoplasts prepared from Group A streptococci by a cell wall-dissolving enzyme. A membrane fraction with identical chemical and serological properties has been obtained by differential centrifugation of mechanically disrupted streptococci. The membrane is chemically distinct from the cell wall and is composed of 72 per cent protein, 26 per cen...